Increased glutamate and NMDA receptor 1 co - localization in chronic painful patellar tendinosis
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چکیده
Increased glutamate and NMDA receptor 1 co-localization in chronic painful patellar tendinosis P. W. Ackermann1, Ø. Lian2, F. Frihagen2, L. Engebretsen2, R. Bahr2, N. Schizas1 1Orthopedic Laboratory, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden; 2Oslo Sports Trauma Research Center, Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway [email protected]
منابع مشابه
Coexistence of up-regulated NMDA receptor 1 and glutamate on nerves, vessels and transformed tenocytes in tendinopathy.
Elevated levels of the neurotransmitter glutamate and the presence of its receptor, N-methyl-d-aspartate receptor type 1 (NMDAR1), have been established in patients with tendinopathy, i.e. chronic tendon pain and degeneration. However, whether NMDAR1 is up- or down-regulated in tendinopathy and co-localized with glutamate is still unexplored. We hypothesize that an alteration in tissue expressi...
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تاریخ انتشار 2002